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Search Results for " proteasome substrates "

3

Compounds

Cat No. Product Name Synonyms Targets
T6941 PI-1840 PI 1840 PARP , Proteasome
PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
T79742 CARM1 degrader-2 Histone Methyltransferase
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 ...
T79741 CARM1 degrader-1 Histone Methyltransferase
PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50=8.1 nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-pro...
TargetMol